How is the study of sequential art explaining the mechanisms that make comics work? Do readers of American comics and Japanese manga use their brains differently? Do comic books naturally create a sense of community among readers in ways text-only books cannot? Do Jack Kirby's machines engage readers in ways they never knew? Neil Cohn (University of California, San Diego), Mathieu Li-Goyette (Université de Montréal), and T. Keith Edmunds (Brandon University) look into the brain, across the real world, and throughout many fictional worlds to examine how comics work for the creators they come from and the readers who consume them.